Description:
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If we have multiples sites on server in chrooted php-fpm pools with opcache activated.
Let's say /var/www/{site1,site2,site3,site4}
Each site contains public_html/index.php, chroot=/var/www/siteX and chdir=/public_html
site1 and site2 are mount points on their own virtual filesystem while the others are on the main filesystem.
So in this case site1 and site2 have the same index.php because of cache, while site3 and site4 get their own one.

So it seems there is a bug on opcache.validate_root when multiple filesystem are used.

Opcache configuration :

; configuration for php ZendOpcache module
; priority=05
zend_extension=opcache.so
opcache.enable=1
opcache.memory_consumption=228
opcache.interned_strings_buffer=20
opcache.max_accelerated_files=130987
opcache.use_cwd=1
opcache.validate_timestamps=0
opcache.revalidate_freq=0
opcache.revalidate_path=1
opcache.save_comments=0
opcache.load_comments=0
opcache.fast_shutdown=1
opcache.enable_file_override=0
opcache.max_file_size=0
opcache.restrict_api="/public_html/hole/nerver.php"
opcache.validate_permission=1
opcache.validate_root=1
opcache.log_verbosity_level=4